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The NFL players with the most safeties in the 2022 season.
| Player | POS | Team | GP | SAF | SCK | DEF INT | PD | SOLO | AST | TOT TKL | TFL | QBH | FF | SCKY |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #1Daron Payne | NT |  WAS | 17 | 1 | 11.5 | 0 | 5 | 27 | 32 | 59 | 16 | 20 | 0 | 81.5 |
| #1Dee Alford | CB |  ATL | 12 | 1 | 0.5 | 1 | 7 | 18 | 7 | 25 | 1 | 1 | ||
| #1Ed Oliver | DT |  BUF | 12 | 1 | 2.5 | 0 | 3 | 15 | 14 | 29 | 7 | 14 | ||
| #1Frank Clark | LB |  KC | 15 | 1 | 5 | 0 | 1 | 21 | 14 | 35 | 6 | 13 | ||
| #1Jermaine Johnson II | DE |  NYJ | 13 | 1 | 2.5 | 0 | 0 | 14 | 11 | 25 | 3 | 5 | ||
| #1Josiah Deguara | TE |  GB | 9 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | ||
| #1Mike Purcell | NT |  DEN | 16 | 1 | 1.5 | 0 | 0 | 16 | 24 | 40 | 1 | 4 | ||
| #1Roy Lopez | DT |  HOU | 15 | 1 | 1 | 0 | 1 | 16 | 16 | 32 | 5 | 3 | ||
| #1Sebastian Joseph-Day | DT |  LAC | 15 | 1 | 2 | 1 | 1 | 22 | 29 | 51 | 8 | 6 |
| 3.5 |
| 13 |
| 32 |
| 14 |
| 0 |
| 2.5 |
| 7 |
| 16 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| Buffalo Bills | 3–1 | .750 | +20 |
 New England Patriots | 2–2 | .500 | -12 |
| New York Jets | 1–3 | .250 | -8 |
 Miami Dolphins | 0–4 | .000 | -55 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Baltimore Ravens | 3–1 | .750 | +20 |
 Cleveland Browns | 3–1 | .750 | -14 |
 Cincinnati Bengals | 2–2 | .500 | +12 |
 Pittsburgh Steelers | 2–2 | .500 | -10 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Jacksonville Jaguars | 3–1 | .750 | +51 |
 Indianapolis Colts | 2–2 | .500 | -2 |
| Houston Texans | 0–4 | .000 | -25 |
 Tennessee Titans | 0–4 | .000 | -28 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| Kansas City Chiefs | 4–0 | 1.000 | +41 |
 Las Vegas Raiders | 3–1 | .750 | +31 |
| Denver Broncos | 2–2 | .500 | -20 |
| Los Angeles Chargers | 0–4 | .000 | -39 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 New York Giants | 3–1 | .750 | +3 |
 Dallas Cowboys | 2–2 | .500 | +10 |
 Philadelphia Eagles | 2–2 | .500 | -18 |
| Washington Commanders | 1–3 | .250 | -34 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Minnesota Vikings | 4–0 | 1.000 | +35 |
 Chicago Bears | 3–1 | .750 | +47 |
 Detroit Lions | 2–2 | .500 | -8 |
| Green Bay Packers | 2–2 | .500 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Carolina Panthers | 2–2 | .500 | +12 |
| Atlanta Falcons | 2–2 | .500 | +4 |
 New Orleans Saints | 1–3 | .250 | -23 |
 Tampa Bay Buccaneers | 0–4 | .000 | -20 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 San Francisco 49ers | 4–0 | 1.000 | +58 |
 Seattle Seahawks | 3–1 | .750 | +32 |
 Los Angeles Rams | 2–2 | .500 | +2 |
 Arizona Cardinals | 1–3 | .250 | -30 |
