12–5 · #2 in AFC East · Lost Divisional RoundChoose season
| Player | Pos | # | College | Debut | Status |
|---|---|---|---|---|---|
| A.J. Epenesa | LB | — | — | 2020 | Active |
| Alec Anderson | OT | — | — | 2024 | Active |
| Andre Jones Jr. | LB | — | — | 2023 | Active |
| Baylon Spector | LB | — | — | 2022 | Active |
| Brad Robbins | P | — | — | 2023 | Active |
| Brandin Cooks | WR | — | — | 2014 | Active |
| Brandon Codrington | CB | — | — | 2024 | Active |
| Cam Lewis | CB | — | — | 2020 | Active |
| Cameron Johnston | P | — | — | 2018 | Active |
| Chase Lundt | OT | — | — | 2025 | Active |
| Christian Benford | CB | — | — | 2022 | Active |
| Cole Bishop | SAF | — | — | 2024 | Active |
| Connor McGovern | G | — | — | 2020 | Active |
| Curtis Samuel | WR | — | — | 2017 | Active |
| Dalton Kincaid | TE | — | — | 2023 | Active |
| Damar Hamlin | SAF | — | — | 2021 | Active |
| Dane Jackson | CB | — | — | 2020 | Active |
| DaQuan Jones | DT | — | — | 2014 | Active |
| Darnell Savage | SAF | — | — | 2019 | Active |
| David Edwards | OT | — | — | 2019 | Active |
| Dawson Knox | TE | — | — | 2019 | Active |
| Deone Walker | DT | — | — | 2025 | Active |
| Dion Dawkins | OT | — | — | 2017 | Active |
| Dorian Strong | CB | — | — | 2025 | Active |
| Dorian Williams | LB | — | — | 2023 | Active |
| Ed Oliver | DT | — | — | 2019 | Active |
| Elijah Moore | WR | — | — | 2021 | Active |
| Gabe Davis | WR | — | — | 2020 | Active |
| Greg Rousseau | LB | — | — | 2021 | Active |
| Ja'Marcus Ingram | CB | — | — | 2022 | Active |
| Jackson Hawes | TE | — | — | 2025 | Active |
| James Cook | RB | — | — | 2022 | Active |
| Javon Solomon | LB | — | — | 2024 | Active |
| Jimmy Ciarlo | LB | — | — | 2025 | Active |
| Joe Andreessen | LB | — | — | 2024 | Active |
| Joey Bosa | DE | — | — | 2016 | Active |
| Jordan Hancock | CB | — | — | 2025 | Active |
| Jordan Phillips | DT | — | — | 2015 | Active |
| Jordan Poyer | FS | — | — | 2013 | Active |
| Josh Allen | QB | — | — | 2018 | Active |
| Josh Palmer | WR | — | — | 2021 | Active |
| Keleki Latu | TE | — | — | 2025 | Active |
| Keon Coleman | WR | — | — | 2024 | Active |
| Keonta Jenkins | LB | — | — | 2025 | Active |
| Khalil Shakir | WR | — | — | 2022 | Active |
| Landon Jackson | DE | — | — | 2025 | Active |
| Larry Ogunjobi | DT | — | — | 2017 | Active |
| Matt Milano | OLB | — | — | 2017 | Active |
| Matt Prater | K | — | — | 2007 | Active |
| Matthew Judon | OLB | — | — | 2016 | Active |
| Maxwell Hairston | CB | — | — | 2025 | Active |
| Mecole Hardman | WR | — | — | 2019 | Active |
| Michael Hoecht | LB | — | — | 2021 | Active |
| Mike Badgley | K | — | — | 2018 | Active |
| Mitch Wishnowsky | P | — | — | 2019 | Active |
| Mitchell Trubisky | QB | — | — | 2017 | Active |
| Morgan Fox | DE | — | — | 2016 | Active |
| O'Cyrus Torrence | G | — | — | 2023 | Active |
| Phidarian Mathis | DT | — | — | 2022 | Active |
| Ray Davis | RB | — | — | 2024 | Active |
| Reggie Gilliam | RB | — | — | 2020 | Active |
| Reid Ferguson | LS | — | — | 2017 | Active |
| Ryan Van Demark | OT | — | — | 2023 | Active |
| Sam Franklin Jr. | SAF | — | — | 2020 | Active |
| Sedrick Van Pran-Granger | C | — | — | 2024 | Active |
| Shaq Thompson | OLB | — | — | 2015 | Active |
| Spencer Brown | OT | — | — | 2021 | Active |
| T.J. Sanders | DT | — | — | 2025 | Active |
| Taron Johnson | CB | — | — | 2018 | Active |
| Taylor Rapp | SAF | — | — | 2019 | Active |
| Terrel Bernard | LB | — | — | 2022 | Active |
| Tre'Davious White | CB | — | — | 2017 | Active |
| Ty Johnson | RB | — | — | 2019 | Active |
| Tylan Grable | OT | — | — | 2024 | Active |
| Tyrell Shavers | WR | — | — | 2024 | Active |
| Zion Logue | DT | — | — | 2024 | Active |
| 3–1 |
| .750 |
| -14 |
| 2–2 | .500 | +12 |
| 2–2 | .500 | -10 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +51 | |
| 2–2 | .500 | -2 | |
| 0–4 | .000 | -25 | |
| 0–4 | .000 | -28 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +41 | |
| 3–1 | .750 | +31 | |
| 2–2 | .500 | -20 | |
| 0–4 | .000 | -39 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +3 | |
| 2–2 | .500 | +10 | |
| 2–2 | .500 | -18 | |
| 1–3 | .250 | -34 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +35 | |
| 3–1 | .750 | +47 | |
| 2–2 | .500 | -8 | |
| 2–2 | .500 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 2–2 | .500 | +12 | |
| 2–2 | .500 | +4 | |
| 1–3 | .250 | -23 | |
| 0–4 | .000 | -20 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +58 | |
| 3–1 | .750 | +32 | |
| 2–2 | .500 | +2 | |
| 1–3 | .250 | -30 |