4–12 · #3 in AFC SouthChoose season
| Player | Pos | # | College | Debut | Status |
|---|---|---|---|---|---|
| A.J. Moore | DB | — | — | 2018 | Active |
| AJ McCarron | QB | — | — | 2015 | Active |
| Andrew Brown | DT | — | — | 2019 | Active |
| Anthony Chesley | CB | — | — | 2020 | Active |
| Auzoyah Alufohai | DT | — | — | 2020 | Active |
| Beau Benzschawel | C | — | — | 2019 | Active |
| Benardrick McKinney | ILB | — | — | 2015 | Active |
| Bradley Roby | CB | — | — | 2014 | Active |
| Brandin Cooks | WR | — | — | 2014 | Active |
| Brandon Dunn | NT | — | — | 2014 | Active |
| Brennan Scarlett | OLB | — | — | 2016 | Active |
| Brent Qvale | G | — | — | 2015 | Active |
| Bryan Anger | P | — | — | 2012 | Active |
| Buddy Howell | RB | — | — | 2018 | Active |
| C.J. Prosise | RB | — | — | 2016 | Active |
| Carlos Watkins | DE | — | — | 2017 | Active |
| Chad Hansen | WR | — | — | 2017 | Active |
| Charles Omenihu | DE | — | — | 2019 | Active |
| Charlie Heck | OT | — | — | 2020 | Active |
| Corey Liuget | DT | — | — | 2011 | Active |
| Cornell Armstrong | DB | — | — | 2018 | Active |
| Cullen Gillaspia | RB | — | — | 2019 | Active |
| Darren Fells | TE | — | — | 2014 | Active |
| David Johnson | RB | — | — | 2015 | Active |
| DeAndre Carter | WR | — | — | 2018 | Active |
| Deshaun Watson | QB | — | — | 2017 | Active |
| Dontrell Hilliard | RB | — | — | 2018 | Active |
| Duke Johnson | RB | — | — | 2015 | Active |
| Dylan Cole | LB | — | — | 2017 | Active |
| Eric Murray | S | — | — | 2016 | Active |
| Greg Mancz | G | — | — | 2015 | Active |
| Isaiah Coulter | WR | — | — | 2020 | Active |
| J.J. Watt | DE | — | — | 2011 | Active |
| Jacob Martin | DE | — | — | 2018 | Active |
| John Reid | CB | — | — | 2020 | Active |
| Jon Weeks | LS | — | — | 2010 | Active |
| Jonathan Greenard | LB | — | — | 2020 | Active |
| Jonathan Owens | SAF | — | — | 2019 | Active |
| Jordan Akins | TE | — | — | 2018 | Active |
| Justin Reid | S | — | — | 2018 | Active |
| Ka'imi Fairbairn | K | — | — | 2017 | Active |
| Kahale Warring | TE | — | — | 2020 | Active |
| Keion Crossen | DB | — | — | 2018 | Active |
| Keke Coutee | WR | — | — | 2018 | Active |
| Kenny Stills | WR | — | — | 2013 | Active |
| Kyle Emanuel | OLB | — | — | 2015 | Active |
| Laremy Tunsil | OT | — | — | 2016 | Active |
| Lonnie Johnson | SAF | — | — | 2019 | Active |
| Mark Fields | CB | — | — | 2019 | Active |
| Max Scharping | G | — | — | 2019 | Active |
| Michael Thomas | DB | — | — | 2013 | Active |
| Nate Hall | LB | — | — | 2020 | Active |
| Nick Martin | C | — | — | 2017 | Active |
| P.J. Hall | DT | — | — | 2018 | Active |
| Peter Kalambayi | LB | — | — | 2018 | Active |
| Pharaoh Brown | TE | — | — | 2017 | Active |
| Phillip Gaines | CB | — | — | 2014 | Active |
| Randall Cobb | WR | — | — | 2011 | Active |
| Roderick Johnson | OT | — | — | 2018 | Active |
| Ross Blacklock | DT | — | — | 2020 | Active |
| Scottie Phillips | RB | — | — | 2020 | Active |
| Senio Kelemete | G | — | — | 2012 | Active |
| Steven Mitchell | WR | — | — | 2018 | Active |
| Tyrell Adams | LB | — | — | 2016 | Active |
| Tytus Howard | OT | — | — | 2019 | Active |
| Vernon Hargreaves III | CB | — | — | 2016 | Active |
| Whitney Mercilus | DE | — | — | 2012 | Active |
| Will Fuller | WR | — | — | 2016 | Active |
| Zach Cunningham | ILB | — | — | 2017 | Active |
| Zach Fulton | G | — | — | 2014 | Active |
| 3–1 |
| .750 |
| -14 |
| 2–2 | .500 | +12 |
| 2–2 | .500 | -10 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +51 | |
| 2–2 | .500 | -2 | |
| 0–4 | .000 | -25 | |
| 0–4 | .000 | -28 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +41 | |
| 3–1 | .750 | +31 | |
| 2–2 | .500 | -20 | |
| 0–4 | .000 | -39 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +3 | |
| 2–2 | .500 | +10 | |
| 2–2 | .500 | -18 | |
| 1–3 | .250 | -34 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +35 | |
| 3–1 | .750 | +47 | |
| 2–2 | .500 | -8 | |
| 2–2 | .500 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 2–2 | .500 | +12 | |
| 2–2 | .500 | +4 | |
| 1–3 | .250 | -23 | |
| 0–4 | .000 | -20 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +58 | |
| 3–1 | .750 | +32 | |
| 2–2 | .500 | +2 | |
| 1–3 | .250 | -30 |