4–13 · #3 in AFC SouthChoose season
| Player | Pos | # | College | Debut | Status |
|---|---|---|---|---|---|
| A.J. Moore | DB | — | — | 2018 | Active |
| Andre Roberts | WR | — | — | 2010 | Active |
| Anthony Miller | WR | — | — | 2018 | Active |
| Antony Auclair | TE | — | — | 2017 | Active |
| Brandin Cooks | WR | — | — | 2014 | Active |
| Brevin Jordan | TE | — | — | 2021 | Active |
| Cameron Johnston | P | — | — | 2018 | Active |
| Charles Omenihu | DE | — | — | 2019 | Active |
| Charlie Heck | OT | — | — | 2020 | Active |
| Chris Conley | WR | — | — | 2015 | Active |
| Chris Moore | WR | — | — | 2016 | Active |
| Chris Smith | LB | — | — | 2014 | Active |
| Christian Kirksey | OLB | — | — | 2014 | Active |
| Cole Toner | OT | — | — | 2016 | Active |
| Connor Strachan | LB | — | — | 2021 | Active |
| Danny Amendola | WR | — | — | 2009 | Active |
| David Johnson | RB | — | — | 2015 | Active |
| Davion Davis | WR | — | — | 2019 | Active |
| Davis Mills | QB | — | — | 2021 | Active |
| DeMarcus Walker | DE | — | — | 2017 | Active |
| Demone Harris | DE | — | — | 2018 | Active |
| Derek Rivers | DE | — | — | 2018 | Active |
| Desmond King | DB | — | — | 2017 | Active |
| Dominik Eberle | K | — | — | 2021 | Active |
| Eric Murray | S | — | — | 2016 | Active |
| Eric Wilson | LB | — | — | 2017 | Active |
| Garret Wallow | LB | — | — | 2021 | Active |
| Geron Christian | OT | — | — | 2018 | Active |
| Grayland Arnold | SAF | — | — | 2020 | Active |
| Hardy Nickerson | MLB | — | — | 2017 | Active |
| Jacob Martin | DE | — | — | 2018 | Active |
| Jaleel Johnson | DT | — | — | 2017 | Active |
| Jalen Camp | WR | — | — | 2021 | Active |
| Jaylen Samuels | RB | — | — | 2018 | Active |
| Jeff Driskel | QB | — | — | 2018 | Active |
| Jimmy Moreland | CB | — | — | 2019 | Active |
| Jimmy Morrissey | C | — | — | 2021 | Active |
| Joe Thomas | OLB | — | — | 2015 | Active |
| Joey Slye | K | — | — | 2019 | Active |
| Jon Weeks | LS | — | — | 2010 | Active |
| Jonathan Greenard | LB | — | — | 2020 | Active |
| Jonathan Owens | SAF | — | — | 2019 | Active |
| Jordan Akins | TE | — | — | 2018 | Active |
| Jordan Jenkins | DE | — | — | 2016 | Active |
| Jordan Steckler | OT | — | — | 2021 | Active |
| Jordan Veasy | WR | — | — | 2021 | Active |
| Josh Watson | LB | — | — | 2019 | Active |
| Justin Britt | C | — | — | 2014 | Active |
| Justin McCray | G | — | — | 2017 | Active |
| Justin Reid | S | — | — | 2018 | Active |
| Ka'imi Fairbairn | K | — | — | 2017 | Active |
| Kamu Grugier-Hill | OLB | — | — | 2016 | Active |
| Kevin Pierre-Louis | LB | — | — | 2014 | Active |
| Lane Taylor | G | — | — | 2013 | Active |
| Laremy Tunsil | OT | — | — | 2016 | Active |
| Lonnie Johnson | SAF | — | — | 2019 | Active |
| Maliek Collins | DT | — | — | 2016 | Active |
| Marcus Cannon | OT | — | — | 2013 | Active |
| Mark Ingram | RB | — | — | 2011 | Active |
| Max Scharping | G | — | — | 2019 | Active |
| Michael Dwumfour | DT | — | — | 2021 | Active |
| Neville Hewitt | LB | — | — | 2015 | Active |
| Nico Collins | WR | — | — | 2021 | Active |
| Paul Quessenberry | TE | — | — | 2021 | Active |
| Pharaoh Brown | TE | — | — | 2017 | Active |
| Phillip Dorsett | WR | — | — | 2015 | Active |
| Phillip Lindsay | RB | — | — | 2018 | Active |
| Rex Burkhead | RB | — | — | 2013 | Active |
| Ron'Dell Carter | LB | — | — | 2020 | Active |
| Ross Blacklock | DT | — | — | 2020 | Active |
| Roy Lopez | DT | — | — | 2021 | Active |
| Royce Freeman | RB | — | — | 2018 | Active |
| Scottie Phillips | RB | — | — | 2020 | Active |
| T.J. Green | DB | — | — | 2016 | Active |
| Tavierre Thomas | SAF | — | — | 2018 | Active |
| Terrance Mitchell | CB | — | — | 2015 | Active |
| Terrence Brooks | FS | — | — | 2014 | Active |
| Tremon Smith | CB | — | — | 2018 | Active |
| Tyrod Taylor | QB | — | — | 2011 | Active |
| Tytus Howard | OT | — | — | 2019 | Active |
| Vernon Hargreaves III | CB | — | — | 2016 | Active |
| Vincent Taylor | DT | — | — | 2017 | Active |
| Whitney Mercilus | DE | — | — | 2012 | Active |
| Xavier Williams | NT | — | — | 2015 | Active |
| Zach Cunningham | ILB | — | — | 2017 | Active |
| 3–1 |
| .750 |
| -14 |
| 2–2 | .500 | +12 |
| 2–2 | .500 | -10 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +51 | |
| 2–2 | .500 | -2 | |
| 0–4 | .000 | -25 | |
| 0–4 | .000 | -28 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +41 | |
| 3–1 | .750 | +31 | |
| 2–2 | .500 | -20 | |
| 0–4 | .000 | -39 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +3 | |
| 2–2 | .500 | +10 | |
| 2–2 | .500 | -18 | |
| 1–3 | .250 | -34 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +35 | |
| 3–1 | .750 | +47 | |
| 2–2 | .500 | -8 | |
| 2–2 | .500 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 2–2 | .500 | +12 | |
| 2–2 | .500 | +4 | |
| 1–3 | .250 | -23 | |
| 0–4 | .000 | -20 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +58 | |
| 3–1 | .750 | +32 | |
| 2–2 | .500 | +2 | |
| 1–3 | .250 | -30 |