7–9 · #3 in AFC WestChoose season
| Player | Pos | # | College | Debut | Status |
|---|---|---|---|---|---|
| Alohi Gilman | SAF | — | — | 2020 | Active |
| Asmar Bilal | LB | — | — | 2020 | Active |
| Austin Ekeler | RB | — | — | 2017 | Active |
| B.J. Bello | LB | — | — | 2017 | Active |
| Brandon Facyson | DB | — | — | 2018 | Active |
| Breiden Fehoko | DT | — | — | 2020 | Active |
| Bryan Bulaga | OT | — | — | 2010 | Active |
| Casey Hayward | CB | — | — | 2012 | Active |
| Chris Harris | CB | — | — | 2011 | Active |
| Cole Christiansen | LB | — | — | 2020 | Active |
| Cole Mazza | LS | — | — | 2019 | Active |
| Cole Toner | OT | — | — | 2016 | Active |
| Cortez Broughton | DT | — | — | 2019 | Active |
| Damion Square | DT | — | — | 2013 | Active |
| Dan Feeney | G | — | — | 2017 | Active |
| Darius Bradwell | RB | — | — | 2020 | Active |
| Denzel Perryman | MLB | — | — | 2015 | Active |
| Desmond King | DB | — | — | 2017 | Active |
| Donald Parham | TE | — | — | 2020 | Active |
| Drue Tranquill | LB | — | — | 2019 | Active |
| Easton Stick | QB | — | — | 2020 | Active |
| Emeke Egbule | LB | — | — | 2019 | Active |
| Forrest Lamp | G | — | — | 2018 | Active |
| Gabe Nabers | FB | — | — | 2020 | Active |
| Hunter Henry | TE | — | — | 2016 | Active |
| Isaac Rochell | DE | — | — | 2017 | Active |
| Jahleel Addae | S | — | — | 2013 | Active |
| Jalen Guyton | WR | — | — | 2019 | Active |
| Jason Moore | WR | — | — | 2019 | Active |
| Jaylen Watkins | FS | — | — | 2014 | Active |
| Jerry Tillery | DT | — | — | 2019 | Active |
| Jessie Lemonier | LB | — | — | 2020 | Active |
| Joe Gaziano | DE | — | — | 2020 | Active |
| Joe Reed | WR | — | — | 2020 | Active |
| Joey Bosa | DE | — | — | 2016 | Active |
| John Brannon | DB | — | — | 2020 | Active |
| Joshua Kelley | RB | — | — | 2020 | Active |
| Justin Herbert | QB | — | — | 2020 | Active |
| Justin Jackson | RB | — | — | 2018 | Active |
| Justin Jones | DT | — | — | 2018 | Active |
| K.J. Hill | WR | — | — | 2020 | Active |
| Kalen Ballage | RB | — | — | 2018 | Active |
| Keenan Allen | WR | — | — | 2013 | Active |
| Kenneth Murray, Jr. | LB | — | — | 2020 | Active |
| Kyzir White | OLB | — | — | 2018 | Active |
| Linval Joseph | DT | — | — | 2010 | Active |
| Malik Jefferson | LB | — | — | 2018 | Active |
| Matt Sokol | TE | — | — | 2020 | Active |
| Melvin Ingram | LB | — | — | 2012 | Active |
| Michael Davis | CB | — | — | 2017 | Active |
| Mike Badgley | K | — | — | 2018 | Active |
| Mike Williams | WR | — | — | 2017 | Active |
| Nasir Adderley | FS | — | — | 2019 | Active |
| Nick Vigil | OLB | — | — | 2016 | Active |
| Quenton Meeks | CB | — | — | 2018 | Active |
| Rayshawn Jenkins | DB | — | — | 2017 | Active |
| Ryan Groy | G | — | — | 2014 | Active |
| Sam Tevi | OT | — | — | 2017 | Active |
| Scott Quessenberry | C | — | — | 2018 | Active |
| Stephen Anderson | TE | — | — | 2016 | Active |
| Storm Norton | OT | — | — | 2018 | Active |
| Tevaughn Campbell | DB | — | — | 2020 | Active |
| Trai Turner | G | — | — | 2014 | Active |
| Trey Pipkins | OT | — | — | 2019 | Active |
| Troymaine Pope | RB | — | — | 2016 | Active |
| Ty Long | P | — | — | 2019 | Active |
| Tyree St. Louis | G | — | — | 2020 | Active |
| Tyrod Taylor | QB | — | — | 2011 | Active |
| Tyron Johnson | WR | — | — | 2020 | Active |
| Uchenna Nwosu | LB | — | — | 2018 | Active |
| Virgil Green | TE | — | — | 2011 | Active |
| 3–1 |
| .750 |
| -14 |
| 2–2 | .500 | +12 |
| 2–2 | .500 | -10 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +51 | |
| 2–2 | .500 | -2 | |
| 0–4 | .000 | -25 | |
| 0–4 | .000 | -28 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +41 | |
| 3–1 | .750 | +31 | |
| 2–2 | .500 | -20 | |
| 0–4 | .000 | -39 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +3 | |
| 2–2 | .500 | +10 | |
| 2–2 | .500 | -18 | |
| 1–3 | .250 | -34 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +35 | |
| 3–1 | .750 | +47 | |
| 2–2 | .500 | -8 | |
| 2–2 | .500 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 2–2 | .500 | +12 | |
| 2–2 | .500 | +4 | |
| 1–3 | .250 | -23 | |
| 0–4 | .000 | -20 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +58 | |
| 3–1 | .750 | +32 | |
| 2–2 | .500 | +2 | |
| 1–3 | .250 | -30 |