10–7 · #2 in NFC West · Lost Divisional RoundChoose season
| Player | Pos | # | College | Debut | Status |
|---|---|---|---|---|---|
| A.J. Arcuri | OT | — | — | 2022 | Active |
| Ahkello Witherspoon | CB | — | — | 2017 | Active |
| Alaric Jackson | OT | — | — | 2021 | Active |
| Alex Ward | LS | — | — | 2023 | Active |
| Beaux Limmer | G | — | — | 2024 | Active |
| Blake Corum | RB | — | — | 2024 | Active |
| Bobby Brown III | DT | — | — | 2021 | Active |
| Braden Fiske | DT | — | — | 2024 | Active |
| Brennan Jackson | LB | — | — | 2024 | Active |
| Byron Young | LB | — | — | 2023 | Active |
| Cam Lampkin | DB | — | — | 2024 | Active |
| Charles Woods | CB | — | — | 2024 | Active |
| Christian Rozeboom | LB | — | — | 2021 | Active |
| Cobie Durant | CB | — | — | 2022 | Active |
| Cody Schrader | RB | — | — | 2024 | Active |
| Colby Parkinson | TE | — | — | 2020 | Active |
| Cooper Kupp | WR | — | — | 2017 | Active |
| Darious Williams | CB | — | — | 2018 | Active |
| Davis Allen | TE | — | — | 2023 | Active |
| Demarcus Robinson | WR | — | — | 2016 | Active |
| Desjuan Johnson | DE | — | — | 2023 | Active |
| Dylan McMahon | C | — | — | 2024 | Active |
| Elias Neal | LB | — | — | 2024 | Active |
| Emmanuel Forbes | CB | — | — | 2023 | Active |
| Ethan Evans | P | — | — | 2023 | Active |
| Geron Christian | OT | — | — | 2018 | Active |
| Hunter Long | TE | — | — | 2021 | Active |
| Jacob Hummel | LB | — | — | 2022 | Active |
| Jared Verse | DE | — | — | 2024 | Active |
| Jaylen McCollough | SAF | — | — | 2024 | Active |
| Jimmy Garoppolo | QB | — | — | 2014 | Active |
| Joe Noteboom | OT | — | — | 2018 | Active |
| John Johnson | DB | — | — | 2017 | Active |
| Jonah Jackson | G | — | — | 2020 | Active |
| Jonah Williams | DE | — | — | 2021 | Active |
| Jordan Whittington | WR | — | — | 2024 | Active |
| Josh Wallace | CB | — | — | 2024 | Active |
| Joshua Karty | K | — | — | 2024 | Active |
| Justin Dedich | OL | — | — | 2024 | Active |
| Kam Curl | SAF | — | — | 2020 | Active |
| Kamren Kinchens | SAF | — | — | 2024 | Active |
| Keir Thomas | LB | — | — | 2022 | Active |
| Kevin Dotson | G | — | — | 2020 | Active |
| Kobie Turner | DE | — | — | 2023 | Active |
| Kyren Williams | RB | — | — | 2022 | Active |
| Logan Bruss | G | — | — | 2024 | Active |
| Matthew Stafford | QB | — | — | 2009 | Active |
| Michael Hoecht | LB | — | — | 2021 | Active |
| Neville Gallimore | DT | — | — | 2020 | Active |
| Nick Hampton | LB | — | — | 2023 | Active |
| Nikola Kalinic | TE | — | — | 2022 | Active |
| Omar Speights | LB | — | — | 2024 | Active |
| Puka Nacua | WR | — | — | 2023 | Active |
| Quentin Lake | SAF | — | — | 2022 | Active |
| Rob Havenstein | OT | — | — | 2015 | Active |
| Ronnie Rivers | RB | — | — | 2022 | Active |
| Russ Yeast | SAF | — | — | 2022 | Active |
| Steve Avila | G | — | — | 2023 | Active |
| Tre'Davious White | CB | — | — | 2017 | Active |
| Troy Reeder | LB | — | — | 2019 | Active |
| Tutu Atwell | WR | — | — | 2021 | Active |
| Ty Zentner | P | — | — | 2023 | Active |
| Tyler Davis | DE | — | — | 2024 | Active |
| Tyler Higbee | TE | — | — | 2016 | Active |
| Tyler Johnson | WR | — | — | 2020 | Active |
| Warren McClendon Jr. | OT | — | — | 2023 | Active |
| Xavier Smith | WR | — | — | 2024 | Active |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Buffalo Bills | 3–1 | .750 | +20 |
 New England Patriots | 2–2 | .500 | -12 |
 New York Jets | 1–3 | .250 | -8 |
 Miami Dolphins | 0–4 | .000 | -55 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Baltimore Ravens | 3–1 | .750 | +20 |
| Cleveland Browns |
| 3–1 |
| .750 |
| -14 |
 Cincinnati Bengals | 2–2 | .500 | +12 |
|---|
 Pittsburgh Steelers | 2–2 | .500 | -10 |
|---|
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Jacksonville Jaguars | 3–1 | .750 | +51 |
 Indianapolis Colts | 2–2 | .500 | -2 |
 Houston Texans | 0–4 | .000 | -25 |
 Tennessee Titans | 0–4 | .000 | -28 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Kansas City Chiefs | 4–0 | 1.000 | +41 |
 Las Vegas Raiders | 3–1 | .750 | +31 |
 Denver Broncos | 2–2 | .500 | -20 |
 Los Angeles Chargers | 0–4 | .000 | -39 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 New York Giants | 3–1 | .750 | +3 |
 Dallas Cowboys | 2–2 | .500 | +10 |
 Philadelphia Eagles | 2–2 | .500 | -18 |
 Washington Commanders | 1–3 | .250 | -34 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Minnesota Vikings | 4–0 | 1.000 | +35 |
 Chicago Bears | 3–1 | .750 | +47 |
 Detroit Lions | 2–2 | .500 | -8 |
 Green Bay Packers | 2–2 | .500 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Carolina Panthers | 2–2 | .500 | +12 |
 Atlanta Falcons | 2–2 | .500 | +4 |
 New Orleans Saints | 1–3 | .250 | -23 |
 Tampa Bay Buccaneers | 0–4 | .000 | -20 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 San Francisco 49ers | 4–0 | 1.000 | +58 |
 Seattle Seahawks | 3–1 | .750 | +32 |
| Los Angeles Rams | 2–2 | .500 | +2 |
 Arizona Cardinals | 1–3 | .250 | -30 |
