2–2 · #3 in NFC WestChoose season
| Player | Pos | # | College | Debut | Status |
|---|---|---|---|---|---|
| Aaron Donald | DL | #99 | Pittsburgh | 2014 | Active |
| Alaric Jackson | OL | #77 | Iowa | 2021 | Active |
| Alex Bachman | WR | #11 | Wake Forest | 2020 | Active |
| Beaux Limmer | OL | #50 | Arkansas | 2024 | Active |
| Bill Murray | OL | #66 | William & Mary | — | Active |
| Blake Corum | RB | #24 | Michigan | 2024 | Active |
| Braden Fiske | DL | #55 | Florida State | 2024 | Active |
| Byron Young | LB | #0 | Tennessee | 2023 | Active |
| CJ Daniels | WR | #6 | Miami | — | Active |
| Colby Parkinson | TE | #84 | Stanford | 2020 | Active |
| Coleman Shelton | OL | #65 | Washington | 2019 | Active |
| Davante Adams | WR | #17 | Fresno State | 2014 | Active |
| David Quessenberry | OL | #68 | San Jose State | 2017 | Active |
| Davis Allen | TE | #87 | Clemson | 2023 | Active |
| Dean Connors | RB | #33 | Houston | 2026 | Active |
| Desjuan Johnson | LB | #94 | Toledo | 2023 | Active |
| Dylan McMahon | OL | #63 | N.C. State | 2024 | Active |
| Emmanuel Forbes | DB | #1 | Mississippi State | 2023 | Active |
| Ethan Evans | P | #42 | Wingate | 2023 | Active |
| Grant Stuard | LB | #44 | Houston | 2021 | Active |
| Harrison Mevis | K | #92 | Missouri | 2025 | Active |
| Jaylen McCollough | DB | #2 | Tennessee | 2024 | Active |
| Jaylen Watson | DB | #35 | Washington State | 2022 | Active |
| Joe Cardona | LS | #49 | Navy | 2015 | Active |
| Jordan Whittington | WR | #88 | Texas | 2024 | Active |
| Josaiah Stewart | LB | #10 | Michigan | 2025 | Active |
| Josh Wallace | DB | #30 | Michigan | 2024 | Active |
| Kam Curl | DB | #3 | Arkansas | 2020 | Active |
| Kamren Kinchens | DB | #5 | Miami | 2024 | Active |
| Kevin Dotson | OL | #69 | Louisiana-Lafayette | 2020 | Active |
| Kobie Turner | DL | #91 | Wake Forest | 2023 | Active |
| Konata Mumpfield | WR | #4 | Pittsburgh | 2025 | Active |
| Kyren Williams | RB | #23 | Notre Dame | 2022 | Active |
| Larrell Murchison | DL | #52 | N.C. State | 2020 | Active |
| Matthew Stafford | QB | #9 | Georgia | 2009 | Active |
| Max Klare | TE | #86 | Ohio State | 2026 | Active |
| Maximus Pulley | DB | #36 | Wofford | 2026 | Active |
| Nate Landman | LB | #53 | Colorado | 2022 | Active |
| Omar Speights | LB | #48 | LSU | 2024 | Active |
| Poona Ford | DL | #97 | Texas | 2018 | Active |
| Puka Nacua | WR | #12 | BYU | 2023 | Active |
| Quentin Lake | DB | #37 | UCLA | 2022 | Active |
| Shaun Dolac | LB | #56 | Buffalo | 2025 | Active |
| Stetson Bennett | QB | #13 | Georgia | 2026 | Active |
| Steve Avila | OL | #73 | TCU | 2023 | Active |
| Trent McDuffie | DB | #22 | Washington | 2022 | Active |
| Tutu Atwell | WR | #8 | Louisville | 2021 | Active |
| Ty Hamilton | DL | #57 | Ohio State | 2025 | Active |
| Ty Simpson | QB | #15 | Alabama | — | Active |
| Tyler Davis | DL | #90 | Clemson | 2024 | Active |
| Tyler Higbee | TE | #89 | Western Kentucky | 2016 | Active |
| Warren McClendon Jr. | OL | #71 | Georgia | 2023 | Active |
| Wesley Bailey | LB | #47 | Louisville | 2026 | Active |
| Austin Blaske | OL | #64 | North Carolina | — | Practice squad |
| Bill Norton | DL | #93 | Texas | — | Practice squad |
| Blake Hance | OL | #72 | Northwestern | 2021 | Practice squad |
| Brennan Presley | WR | #81 | Oklahoma State | 2025 | Practice squad |
| Cam Lampkin | DB | #21 | Washington State | 2024 | Practice squad |
| Dan Villari | TE | #83 | Syracuse | — | Practice squad |
| Daniel Rickert | LB | #40 | Virginia | — | Reserve |
| Darryl Peterson III | LB | #59 | Wisconsin | 2026 | Practice squad |
| Eddie Walls III | LB | #51 | Houston | — | Reserve |
| Elias Neal | LB | #58 | Marshall | 2024 | Practice squad |
| Eric Kendricks | LB | #43 | UCLA | 2015 | Practice squad |
| Jack Bouwmeester | P | #14 | Texas | — | Practice squad |
| Jamie Sheriff | LB | #54 | South Alabama | 2024 | Practice squad |
| Jaxson Moi | DL | #98 | Tennessee | — | Practice squad |
| Jordan Waters | RB | #32 | N.C. State | — | Practice squad |
| Justin Dedich | OL | #67 | USC | 2024 | Reserve |
| Keagen Trost | OL | #79 | Missouri | — | Reserve |
| Keir Thomas | LB | #11 | Florida State | 2022 | Reserve |
| Matthew Caldwell | QB | #16 | Texas | — | Reserve |
| Myles Garrett | LB | #95 | Texas A&M | 2017 | Reserve |
| Nick Andersen | DB | #45 | Wake Forest | — | Practice squad |
| Nyzier Fourqurean | DB | #25 | Wisconsin | — | Practice squad |
| Ronnie Rivers | RB | #20 | Fresno State | 2022 | Reserve |
| Tanner Ingle | DB | #34 | N.C. State | 2025 | Practice squad |
| Terrance Ferguson | TE | #18 | Oregon | 2025 | Reserve |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Buffalo Bills | 3–1 | .750 | +20 |
 New England Patriots | 2–2 | .500 | -12 |
 New York Jets | 1–3 | .250 | -8 |
 Miami Dolphins | 0–4 | .000 | -55 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Baltimore Ravens | 3–1 | .750 | +20 |
| Cleveland Browns |
| 3–1 |
| .750 |
| -14 |
 Cincinnati Bengals | 2–2 | .500 | +12 |
|---|
 Pittsburgh Steelers | 2–2 | .500 | -10 |
|---|
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Jacksonville Jaguars | 3–1 | .750 | +51 |
 Indianapolis Colts | 2–2 | .500 | -2 |
 Houston Texans | 0–4 | .000 | -25 |
 Tennessee Titans | 0–4 | .000 | -28 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Kansas City Chiefs | 4–0 | 1.000 | +41 |
 Las Vegas Raiders | 3–1 | .750 | +31 |
 Denver Broncos | 2–2 | .500 | -20 |
 Los Angeles Chargers | 0–4 | .000 | -39 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 New York Giants | 3–1 | .750 | +3 |
 Dallas Cowboys | 2–2 | .500 | +10 |
 Philadelphia Eagles | 2–2 | .500 | -18 |
 Washington Commanders | 1–3 | .250 | -34 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Minnesota Vikings | 4–0 | 1.000 | +35 |
 Chicago Bears | 3–1 | .750 | +47 |
 Detroit Lions | 2–2 | .500 | -8 |
 Green Bay Packers | 2–2 | .500 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Carolina Panthers | 2–2 | .500 | +12 |
 Atlanta Falcons | 2–2 | .500 | +4 |
 New Orleans Saints | 1–3 | .250 | -23 |
 Tampa Bay Buccaneers | 0–4 | .000 | -20 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 San Francisco 49ers | 4–0 | 1.000 | +58 |
 Seattle Seahawks | 3–1 | .750 | +32 |
| Los Angeles Rams | 2–2 | .500 | +2 |
 Arizona Cardinals | 1–3 | .250 | -30 |
