13–3 · #1 in NFC South · Super Bowl XLIV ChampionChoose season
| Player | Pos | # | College | Debut | Status |
|---|---|---|---|---|---|
| Anthony Hargrove | DE | — | — | 2004 | Active |
| Anthony Waters | LB | — | — | 2008 | Active |
| Bobby McCray | DE | — | — | 2004 | Active |
| Buck Ortega | TE | — | — | 2008 | Active |
| Carl Nicks | G | — | — | 2008 | Active |
| Charles Grant | DE | — | — | 2002 | Active |
| Chris McAlister | DB | — | — | — | Active |
| Chris Reis | FS | — | — | 2007 | Active |
| Courtney Roby | WR | — | — | 2005 | Active |
| Darnell Dinkins | TE | — | — | 2002 | Active |
| Darren Sharper | FS | — | — | — | Active |
| David Thomas | TE | — | — | 2006 | Active |
| DeMario Pressley | DT | — | — | 2009 | Active |
| Devery Henderson | WR | — | — | 2005 | Active |
| Drew Brees | QB | — | — | 2001 | Active |
| Garrett Hartley | K | — | — | 2008 | Active |
| Heath Evans | FB | — | — | 2001 | Active |
| Jabari Greer | CB | — | — | 2004 | Active |
| Jahri Evans | G | — | — | 2006 | Active |
| Jamar Nesbit | G | — | — | — | Active |
| Jason Kyle | LS | — | — | — | Active |
| Jeff Charleston | DE | — | — | 2007 | Active |
| Jeremy Shockey | TE | — | — | 2002 | Active |
| Jermon Bushrod | OT | — | — | 2009 | Active |
| Jo-Lonn Dunbar | OLB | — | — | 2008 | Active |
| John Carney | K | — | — | — | Active |
| Jonathan Casillas | OLB | — | — | 2009 | Active |
| Jonathan Goodwin | C | — | — | 2003 | Active |
| Jonathan Stinchcomb | OT | — | — | 2006 | Active |
| Jonathan Vilma | OLB | — | — | 2004 | Active |
| Kendrick Clancy | NT | — | — | — | Active |
| Kyle Eckel | RB | — | — | 2007 | Active |
| Lance Moore | WR | — | — | 2006 | Active |
| Leigh Torrence | DB | — | — | 2005 | Active |
| Lynell Hamilton | RB | — | — | 2009 | Active |
| Malcolm Jenkins | S | — | — | 2009 | Active |
| Marcus Mailei | FB | — | — | 2009 | Active |
| Mark Brunell | QB | — | — | — | Active |
| Marques Colston | WR | — | — | 2006 | Active |
| Marvin Mitchell | OLB | — | — | 2007 | Active |
| Mike Bell | RB | — | — | 2006 | Active |
| Mike McKenzie | CB | — | — | — | Active |
| Pierre Thomas | RB | — | — | 2007 | Active |
| Pierson Prioleau | S | — | — | — | Active |
| Randall Gay | CB | — | — | 2004 | Active |
| Reggie Bush | RB | — | — | 2006 | Active |
| Remi Ayodele | DT | — | — | 2007 | Active |
| Robert Meachem | WR | — | — | 2008 | Active |
| Rodney Leisle | DT | — | — | 2004 | Active |
| Roman Harper | S | — | — | 2006 | Active |
| Scott Fujita | OLB | — | — | 2002 | Active |
| Scott Shanle | OLB | — | — | 2003 | Active |
| Sedrick Ellis | DT | — | — | 2008 | Active |
| Thomas Morstead | P | — | — | 2009 | Active |
| Tory Humphrey | TE | — | — | 2006 | Active |
| Tracy Porter | CB | — | — | 2008 | Active |
| Troy Evans | OLB | — | — | 2002 | Active |
| Usama Young | S | — | — | 2007 | Active |
| Will Smith | LB | — | — | 2004 | Active |
| Zach Strief | OT | — | — | 2006 | Active |
| 3–1 |
| .750 |
| -14 |
| 2–2 | .500 | +12 |
| 2–2 | .500 | -10 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +51 | |
| 2–2 | .500 | -2 | |
| 0–4 | .000 | -25 | |
| 0–4 | .000 | -28 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +41 | |
| 3–1 | .750 | +31 | |
| 2–2 | .500 | -20 | |
| 0–4 | .000 | -39 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +3 | |
| 2–2 | .500 | +10 | |
| 2–2 | .500 | -18 | |
| 1–3 | .250 | -34 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +35 | |
| 3–1 | .750 | +47 | |
| 2–2 | .500 | -8 | |
| 2–2 | .500 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 2–2 | .500 | +12 | |
| 2–2 | .500 | +4 | |
| 1–3 | .250 | -23 | |
| 0–4 | .000 | -20 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +58 | |
| 3–1 | .750 | +32 | |
| 2–2 | .500 | +2 | |
| 1–3 | .250 | -30 |