12–4 · #1 in AFC North · Lost Wild CardChoose season
| Player | Pos | # | College | Debut | Status |
|---|---|---|---|---|---|
| Alejandro Villanueva | OT | — | — | 2015 | Active |
| Alex Highsmith | LB | — | — | 2020 | Active |
| Anthony McFarland | RB | — | — | 2020 | Active |
| Antoine Brooks Jr. | SAF | — | — | 2020 | Active |
| Avery Williamson | ILB | — | — | 2014 | Active |
| Ben Roethlisberger | QB | — | — | 2004 | Active |
| Benny Snell | RB | — | — | 2019 | Active |
| Bud Dupree | OLB | — | — | 2015 | Active |
| Cameron Heyward | DE | — | — | 2011 | Active |
| Cameron Sutton | CB | — | — | 2017 | Active |
| Carlos Davis | DT | — | — | 2020 | Active |
| Cassius Marsh | LB | — | — | 2014 | Active |
| Chase Claypool | WR | — | — | 2020 | Active |
| Chris Boswell | K | — | — | 2015 | Active |
| Chris Wormley | NT | — | — | 2017 | Active |
| Chukwuma Okorafor | OT | — | — | 2018 | Active |
| David DeCastro | G | — | — | 2012 | Active |
| Deon Cain | WR | — | — | 2019 | Active |
| Derek Watt | FB | — | — | 2016 | Active |
| Derwin Gray | OT | — | — | 2020 | Active |
| Devin Bush | LB | — | — | 2019 | Active |
| Diontae Johnson | WR | — | — | 2019 | Active |
| Dustin Colquitt | P | — | — | 2005 | Active |
| Eric Ebron | TE | — | — | 2014 | Active |
| Henry Mondeaux | DT | — | — | 2020 | Active |
| Isaiah Buggs | DT | — | — | 2019 | Active |
| J.C. Hassenauer | C | — | — | 2020 | Active |
| James Conner | RB | — | — | 2017 | Active |
| James Pierre | CB | — | — | 2020 | Active |
| James Washington | WR | — | — | 2018 | Active |
| Jay Elliott | LB | — | — | 2014 | Active |
| Jaylen Samuels | RB | — | — | 2018 | Active |
| Jerald Hawkins | OT | — | — | 2017 | Active |
| Joe Haden | CB | — | — | 2010 | Active |
| Jordan Berry | P | — | — | 2015 | Active |
| Jordan Dangerfield | SAF | — | — | 2016 | Active |
| Joshua Dobbs | QB | — | — | 2018 | Active |
| JuJu Smith-Schuster | WR | — | — | 2017 | Active |
| Justin Layne | CB | — | — | 2019 | Active |
| Kameron Canaday | LS | — | — | 2016 | Active |
| Kevin Dotson | G | — | — | 2020 | Active |
| Kevin Rader | TE | — | — | 2020 | Active |
| Marcus Allen | LB | — | — | 2018 | Active |
| Mason Rudolph | QB | — | — | 2019 | Active |
| Matt Feiler | G | — | — | 2017 | Active |
| Matthew Wright | K | — | — | 2020 | Active |
| Maurkice Pouncey | C | — | — | 2010 | Active |
| Mike Hilton | CB | — | — | 2017 | Active |
| Minkah Fitzpatrick | FS | — | — | 2018 | Active |
| Ola Adeniyi | OLB | — | — | 2018 | Active |
| Ray-Ray McCloud | WR | — | — | 2018 | Active |
| Robert Spillane | LB | — | — | 2018 | Active |
| Sean Davis | FS | — | — | 2016 | Active |
| Stefen Wisniewski | G | — | — | 2011 | Active |
| Stephon Tuitt | DE | — | — | 2014 | Active |
| Steven Nelson | CB | — | — | 2015 | Active |
| T.J. Watt | OLB | — | — | 2017 | Active |
| Tegray Scales | LB | — | — | 2020 | Active |
| Terrell Edmunds | S | — | — | 2018 | Active |
| Trey Edmunds | RB | — | — | 2017 | Active |
| Tyson Alualu | DE | — | — | 2010 | Active |
| Ulysees Gilbert | LB | — | — | 2019 | Active |
| Vance McDonald | TE | — | — | 2013 | Active |
| Vince Williams | ILB | — | — | 2013 | Active |
| Wendell Smallwood | RB | — | — | 2016 | Active |
| Zach Banner | OT | — | — | 2017 | Active |
| Zach Gentry | TE | — | — | 2019 | Active |
| 3–1 |
| .750 |
| -14 |
| 2–2 | .500 | +12 |
| 2–2 | .500 | -10 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +51 | |
| 2–2 | .500 | -2 | |
| 0–4 | .000 | -25 | |
| 0–4 | .000 | -28 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +41 | |
| 3–1 | .750 | +31 | |
| 2–2 | .500 | -20 | |
| 0–4 | .000 | -39 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 3–1 | .750 | +3 | |
| 2–2 | .500 | +10 | |
| 2–2 | .500 | -18 | |
| 1–3 | .250 | -34 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +35 | |
| 3–1 | .750 | +47 | |
| 2–2 | .500 | -8 | |
| 2–2 | .500 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 2–2 | .500 | +12 | |
| 2–2 | .500 | +4 | |
| 1–3 | .250 | -23 | |
| 0–4 | .000 | -20 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| 4–0 | 1.000 | +58 | |
| 3–1 | .750 | +32 | |
| 2–2 | .500 | +2 | |
| 1–3 | .250 | -30 |