3–1 · #2 in NFC WestChoose season
| Player | Pos | # | College | Debut | Status |
|---|---|---|---|---|---|
| Abraham Lucas | OL | #72 | Washington State | 2022 | Active |
| AJ Barner | TE | #88 | Michigan | 2024 | Active |
| AJ Finley | DB | #30 | Mississippi | 2023 | Active |
| Avery Smith | DB | #27 | Toledo | 2026 | Active |
| Beau Stephens | OL | #70 | Iowa | 2026 | Active |
| Brady Russell | RB | #38 | Colorado | 2023 | Active |
| Brandon Pili | DL | #95 | USC | 2023 | Active |
| Byron Murphy II | DL | #91 | Texas | 2024 | Active |
| Charles Cross | OL | #67 | Mississippi State | 2022 | Active |
| Chazz Surratt | LB | #44 | North Carolina | 2021 | Active |
| Chris Stoll | LS | #41 | Penn State | 2023 | Active |
| Christian Haynes | OL | #64 | Connecticut | 2024 | Active |
| Connor O'Toole | LB | #57 | Utah | 2025 | Active |
| Cooper Kupp | WR | #10 | Eastern Washington | 2017 | Active |
| Dante Fowler Jr. | LB | #56 | Florida | 2016 | Active |
| DeMarcus Lawrence | LB | #0 | Boise State | 2014 | Active |
| Derick Hall | LB | #58 | Auburn | 2023 | Active |
| Devon Witherspoon | DB | #21 | Illinois | 2023 | Active |
| Drake Thomas | LB | #32 | N.C. State | 2023 | Active |
| Drew Lock | QB | #2 | Missouri | 2019 | Active |
| Elijah Arroyo | TE | #18 | Miami | 2025 | Active |
| Emanuel Wilson | RB | #23 | FVSC | 2023 | Active |
| Eric Saubert | TE | #81 | Drake | 2017 | Active |
| Ernest Jones | LB | #13 | South Carolina | 2021 | Active |
| George Holani | RB | #36 | Boise State | 2024 | Active |
| Grey Zabel | OL | #76 | North Dakota State | 2025 | Active |
| Jalen Milroe | QB | #6 | Alabama | 2025 | Active |
| Jalen Sundell | OL | #61 | North Dakota State | 2024 | Active |
| Jarran Reed | DL | #90 | Alabama | 2016 | Active |
| Jason Myers | K | #5 | Marist | 2015 | Active |
| Jaxon Smith-Njigba | WR | #11 | Ohio State | 2023 | Active |
| Josh Jobe | DB | #29 | Alabama | 2022 | Active |
| Josh Jones | OL | #74 | Houston | 2020 | Active |
| Julian Love | DB | #20 | Notre Dame | 2019 | Active |
| Julian Neal | DB | #1 | Arkansas | 2026 | Active |
| Leonard Williams | DL | #99 | USC | 2015 | Active |
| Michael Dickson | P | #4 | Texas | 2018 | Active |
| Mike Morris | DL | #94 | Michigan | 2023 | Active |
| Montorie Foster Jr | WR | #87 | Michigan State | 2026 | Active |
| Nehemiah Pritchett | DB | #28 | Auburn | 2024 | Active |
| Nick Emmanwori | DB | #3 | South Carolina | 2025 | Active |
| Nick Kallerup | TE | #89 | Minnesota | 2025 | Active |
| Olu Oluwatimi | OL | #55 | Michigan | 2023 | Active |
| Patrick O'Connell | LB | #52 | Montana | 2023 | Active |
| Rashid Shaheed | WR | #22 | Weber State | 2022 | Active |
| Robert Henry Jr. | RB | #30 | Texas-San Antonio | — | Active |
| Rodney Thomas | DB | #24 | Yale | 2022 | Active |
| Rylie Mills | DL | #98 | Notre Dame | 2025 | Active |
| Sam Darnold | QB | #14 | USC | 2018 | Active |
| Tory Horton | WR | #15 | Colorado State | 2025 | Active |
| Ty Okada | DB | #39 | Montana State | 2023 | Active |
| Tyrice Knight | LB | #48 | Texas-El Paso | 2024 | Active |
| Uchenna Nwosu | LB | #7 | USC | 2018 | Active |
| Velus Jones Jr. | RB | #33 | Tennessee | 2022 | Active |
| Aidan Hubbard | LB | #93 | Northwestern | — | Practice squad |
| Andre Fuller | DB | #35 | Toledo | — | Practice squad |
| Anthony Bradford | OL | #75 | LSU | 2023 | Reserve |
| Bobby Hart | OL | #68 | Florida State | 2015 | Practice squad |
| Bud Clark | DB | #9 | TCU | — | Reserve |
| Deven Eastern | DL | #97 | Minnesota | — | Practice squad |
| Dontae McMillan | RB | #36 | — | — | Practice squad |
| Emmanuel Henderson Jr. | WR | #84 | Kansas | — | Practice squad |
| Evan Beerntsen | OL | #60 | Northwestern | — | Practice squad |
| Federico Maranges | OL | #62 | Florida Atlantic | — | Practice squad |
| Gary Smith III | DL | #77 | UCLA | — | Practice squad |
| Irvin Charles | WR | #85 | IPU | 2023 | Reserve |
| Jacardia Wright | RB | #31 | Missouri State | 2025 | Practice squad |
| Jadarian Price | RB | #8 | Notre Dame | 2026 | Reserve |
| Jake Bobo | WR | #19 | UCLA | 2023 | Reserve |
| Jimmy Ciarlo | LB | #46 | Army | 2025 | Practice squad |
| Logan Brown | OL | #73 | Kansas | — | Practice squad |
| Malick Meiga | WR | #83 | Coastal Carolina | — | Practice squad |
| Mason Richman | OL | #78 | Iowa | 2025 | Reserve |
| Maxen Hook | DB | #43 | Toledo | 2026 | Practice squad |
| Michael Dansby | DB | #37 | Arizona | — | Practice squad |
| Ricky White III | WR | #86 | UNLV | 2025 | Practice squad |
| Robbie Ouzts | RB | #40 | Alabama | 2025 | Reserve |
| Terrion Arnold | DB | #17 | Alabama | 2024 | Exempt |
| Trevon Diggs | DB | #16 | Alabama | 2020 | Practice squad |
| Zach Charbonnet | RB | #26 | UCLA | 2023 | Reserve |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Buffalo Bills | 3–1 | .750 | +20 |
 New England Patriots | 2–2 | .500 | -12 |
 New York Jets | 1–3 | .250 | -8 |
 Miami Dolphins | 0–4 | .000 | -55 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Baltimore Ravens | 3–1 | .750 | +20 |
| Cleveland Browns |
| 3–1 |
| .750 |
| -14 |
 Cincinnati Bengals | 2–2 | .500 | +12 |
|---|
 Pittsburgh Steelers | 2–2 | .500 | -10 |
|---|
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Jacksonville Jaguars | 3–1 | .750 | +51 |
 Indianapolis Colts | 2–2 | .500 | -2 |
 Houston Texans | 0–4 | .000 | -25 |
 Tennessee Titans | 0–4 | .000 | -28 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Kansas City Chiefs | 4–0 | 1.000 | +41 |
 Las Vegas Raiders | 3–1 | .750 | +31 |
 Denver Broncos | 2–2 | .500 | -20 |
 Los Angeles Chargers | 0–4 | .000 | -39 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 New York Giants | 3–1 | .750 | +3 |
 Dallas Cowboys | 2–2 | .500 | +10 |
 Philadelphia Eagles | 2–2 | .500 | -18 |
 Washington Commanders | 1–3 | .250 | -34 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Minnesota Vikings | 4–0 | 1.000 | +35 |
 Chicago Bears | 3–1 | .750 | +47 |
 Detroit Lions | 2–2 | .500 | -8 |
 Green Bay Packers | 2–2 | .500 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Carolina Panthers | 2–2 | .500 | +12 |
 Atlanta Falcons | 2–2 | .500 | +4 |
 New Orleans Saints | 1–3 | .250 | -23 |
 Tampa Bay Buccaneers | 0–4 | .000 | -20 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 San Francisco 49ers | 4–0 | 1.000 | +58 |
| Seattle Seahawks | 3–1 | .750 | +32 |
 Los Angeles Rams | 2–2 | .500 | +2 |
 Arizona Cardinals | 1–3 | .250 | -30 |
