49ers at Colts: 48–27
49ersSF10–4
Week 16 December 22, 2025
4827
Final
ColtsIND8–6
Box score
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Passing
3 players| Player | Team | Pos | ||||||
|---|---|---|---|---|---|---|---|---|
| Brock Purdy | SF | QB | ||||||
| Philip Rivers | IND | QB | ||||||
| Riley Leonard | IND | QB |
Rushing
7 players| Player | Team | Pos | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Christian McCaffrey | SF | RB | ||||||||
| Jonathan Taylor | IND | RB | ||||||||
| Brian Robinson | SF | RB | ||||||||
| Brock Purdy | SF | QB | ||||||||
| Tyler Goodson | IND | RB | ||||||||
| Josh Downs | IND | WR | ||||||||
| Mac Jones | SF | QB |
Receiving
17 players| Player | Team | Pos | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| George Kittle | SF | TE | ||||||||||||
| Alec Pierce | IND | WR | ||||||||||||
| Jauan Jennings | SF | WR | ||||||||||||
| Josh Downs | IND | WR | ||||||||||||
| Jonathan Taylor | IND | RB | ||||||||||||
| Michael Pittman | IND | WR | ||||||||||||
| Tyler Warren | IND | TE | ||||||||||||
| Christian McCaffrey | SF | RB | ||||||||||||
| Kendrick Bourne | SF | WR | ||||||||||||
| Demarcus Robinson | SF | WR | ||||||||||||
| Skyy Moore | SF | WR | ||||||||||||
| Mo Alie-Cox | IND | TE | ||||||||||||
| Andrew Ogletree | IND | TE | ||||||||||||
| Jake Tonges | SF | TE | ||||||||||||
| Ameer Abdullah | IND | RB | ||||||||||||
| Brian Robinson | SF | RB | ||||||||||||
| Coleman Owen | IND | WR |
Defense
38 players| Player | Team | Pos | ||||||
|---|---|---|---|---|---|---|---|---|
| Alfred Collins | SF | DT | ||||||
| CJ West | SF | DT | ||||||
| Laiatu Latu | IND | DE | ||||||
| Austin Ajiake | IND | LB | ||||||
| Bryce Huff | SF | DE | ||||||
| Cameron Mitchell | IND | DB | ||||||
| Camryn Bynum | IND | SAF | ||||||
| Clelin Ferrell | SF | DE | ||||||
| Darrell Luter Jr. | SF | CB | ||||||
| Dee Winters | SF | LB | ||||||
| DeForest Buckner | IND | DT | ||||||
| Deommodore Lenoir | SF | CB | ||||||
| Eli Apple | SF | CB | ||||||
| Eric Johnson | IND | DT | ||||||
| Eric Kendricks | SF | MLB | ||||||
| George Odum | IND | DB | ||||||
| Germaine Pratt | IND | LB | ||||||
| Grover Stewart | IND | DT | ||||||
| Jaylon Jones | IND | DB | ||||||
| Ji'Ayir Brown | SF | SAF | ||||||
| Johnathan Edwards | IND | DB | ||||||
| Kalia Davis | SF | DT | ||||||
| Keion White | SF | DE | ||||||
| Kenny Moore II | IND | CB | ||||||
| Kwity Paye | IND | DE | ||||||
| Luke Gifford | SF | LB | ||||||
| Malik Mustapha | SF | SAF | ||||||
| Marques Sigle | SF | SAF | ||||||
| Mekhi Blackmon | IND | DB | ||||||
| Neville Gallimore | IND | DT | ||||||
| Nick Cross | IND | SAF | ||||||
| Sam Okuayinonu | SF | DT | ||||||
| Samson Ebukam | IND | DE | ||||||
| Segun Olubi | IND | LB | ||||||
| Tatum Bethune | SF | LB | ||||||
| Tyquan Lewis | IND | DE | ||||||
| Upton Stout | SF | CB | ||||||
| Zaire Franklin | IND | OLB |
Special teams
8 players| Player | Team | Pos | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Skyy Moore | SF | WR | ||||||||
| Coleman Owen | IND | WR | ||||||||
| Tyler Goodson | IND | RB | ||||||||
| Brian Robinson | SF | RB | ||||||||
| Ameer Abdullah | IND | RB | ||||||||
| Blake Grupe | IND | K | ||||||||
| Eddy Pineiro | SF | K | ||||||||
| Rigoberto Sanchez | IND | P |
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